| distance | reference number | name | latitude | longitude |
| 157.9 | 2532 | Rhems, Black Mingo Creek, Black River, South Caroli | 33.6033 | -79.4267 |
| 158.1 | 127 | Bacon Bridge, Ashley River, South Carolina | 32.9583 | -80.2033 |
| 159.0 | 2253 | Pimlico, West Branch, Cooper River, South Carolina | 33.095 | -79.9533 |
| 159.3 | 1413 | Jamestown Bridge, Santee River, South Carolina | 33.305 | -79.6783 |
| 160.4 | 703 | Cuckolds Creek, Combahee River, South Carolina | 32.7133 | -80.695 |
| 160.5 | 1906 | Mt. Pleasant Plantation, Great Pee Dee River, Black | 33.495 | -79.4617 |
| 160.7 | 409 | Canaday Landing, south of, Edisto River, South Caro | 32.8133 | -80.4067 |
| 160.8 | 2115 | Old Rice Mill, West Branch, Cooper River, South Car | 33.0783 | -79.925 |
| 161.1 | 1171 | Greggs Landing, Matceba Gardens, Ashley River, Sout | 32.9283 | -80.155 |
| 161.3 | 99 | Ashepoo, Ashepoo River, South Carolina | 32.7433 | -80.5567 |
| 161.4 | 836 | Dupont, Dean Hall, Cooper River, South Carolina | 33.0583 | -79.9367 |
| 161.4 | 286 | Bluff Plantation, Combahee River, South Carolina | 32.6833 | -80.7383 |
| 162.3 | 3368 | Winea Plantation, Great Pee Dee River, Black River, | 33.535 | -79.3883 |
| 162.5 | 302 | Bonneau Ferry, East Branch, Cooper River, South Car | 33.0717 | -79.8833 |
| 163.3 | 2539 | Richmond Plantation, East Branch, Cooper River, Sou | 33.0767 | -79.855 |
| 163.5 | 278 | Blessing Plantation, East Branch, Cooper River, Sou | 33.055 | -79.88 |
| 163.9 | 3148 | Tulifiny River, I-95 bridge, Broad River, South Car | 32.6017 | -80.9033 |
| 164.1 | 2486 | Quinby Creek bridge, East Branch, Cooper River, Sou | 33.095 | -79.8083 |
| 164.2 | 3167 | U.S. 17 Bridge, Combahee River, South Carolina | 32.6517 | -80.6833 |
| 164.3 | 1090 | General Dynamics Pier, Cooper River, South Carolina | 33.0083 | -79.9233 |
| 164.3 | 1091 | General Dynamics Pier, Cooper River, South Carolina | 33.0083 | -79.9233 |
| 164.5 | 125 | Back River Reservoir, West Branch, Cooper River, So | 32.995 | -79.9367 |
| 165.3 | 267 | Black River (south of Dunbar), South Carolina | 33.5117 | -79.3417 |
| 165.4 | 2220 | Penny Creek, south of, Edisto River, South Carolina | 32.715 | -80.4367 |
| 166.0 | 1213 | Hanahan, Turkey Creek, Goose Creek, Cooper River, S | 32.9183 | -80.0117 |